Department of Cardiovascular Medicine, Saga University, 5-5-1 Nabeshima, Saga, 849-8501, Japan. tanakaa2@cc.saga-u.ac.jp. Department of Diabetes, Endocrinology, and Metabolism, Fukushima Medical University, Fukushima, Japan. Department of Cardiovascular Medicine, JR Hiroshima Hospital, Hiroshima, Japan. First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan, Kitakyusyu, Japan. Department of Endocrinology and Metabolism, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan. Department of Cardiology, Dokkyo Medical University Saitama Medical Center, Koshigaya, Japan. Department of Cardiovascular Medicine, Dokkyo Medical University School of Medicine, Mibu, Japan. Department of Cardiology, Tokyo Medical University, Tokyo, Japan. Department of Clinical Pharmacology and Therapeutics, University of the Ryukyus, Nishihara, Japan. Department of Cardiovascular Regeneration and Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan. Department of Cardiovascular Medicine, Saga University, 5-5-1 Nabeshima, Saga, 849-8501, Japan. node@c.saga-u.ac.jp.